Second City

From the White Wolf Wiki, the most complete White Wolf reference

After the Great Flood, the surviving vampires (by now living on a rich diet of each other's vitae), reassembled while the descendants of Noah spread across the earth. The surviving undead, consisting of the modern Antediluvians and the Second Generation co-opted a human city, turning it into a smaller version of Enoch. This city, never granted a name, eventually collapsed under civil war - the Second Generation were slain and Caine returned to judge his descendants, cursing each of the clans with a distinct weakness and then shattering the city.

The Erciyes Fragments imply that the curse also introduced the limit of Generation and before this all vampires had equal potential. Caine may have intended Generation to force a form of hierarchy on the undead, for what good it did.